Clinical Chemistry
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Clinical Chemistry 20: 502-504, 1974;
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Clinical Chemistry, Vol 20, 502-504, Copyright © 1974 by the American Association for Clinical Chemistry

Advantages and Disadvantages of Nephelometric Measurement of Serum Lipids

Daniel M. Baer 1

1 Department of Pathology, Kaiser Foundation Hospital, Portland, Ore. 97217.

Several technical difficulties diminish the usefulness of serum triglyceride estimation by the method of Stone and Thorp [Clin. Chim. Acta 14, 812 (1966)]. An artificial and somewhat unstable material is used in the standardization. Falsely elevated readings caused by scratched cuvettes are a frequent problem. Conventional quality-control procedures cannot be used because stable preparations are not available. Specimen stability is a greater problem than with conventional chemical methods. In spite of these difficulties, the method can be useful, if its limitations are recognized, in measurements made on nonfasting individuals.


Key Words: nephelometry vs. fluorometry

Submitted on December 18, 1973
Accepted on February 7, 1974






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Copyright © 1974 by the American Association for Clinical Chemistry.