Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 20: 595-602, 1974;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Carey, R. N.
Right arrow Articles by Westgard, J. O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Carey, R. N.
Right arrow Articles by Westgard, J. O.

Clinical Chemistry, Vol 20, 595-602, Copyright © 1974 by the American Association for Clinical Chemistry

Evaluation of the Adaptation of the Glucose Oxidase/Peroxidase-3-Methyl-2-benzothiazolinone hydrazone-N, N-Dimethylaniline Procedure to the Technicon "SMA 12/60," and Comparison with Other Automated Methods for Glucose

R. Neill Carey 1, Donald Feldbruegge 1, and James O. Westgard 1

1 University of Wisconsin Center for Health Sciences, Departments of Pathology and Medicine, Madison, Wis. 53706.

We have evaluated the Technicon SMA 12/60 modification of a glucose oxidase/peroxidase-3-methyl-2-benzothiazolinone hydrazone-N, N-dimethylaniline method, and find it acceptable. Added bilirubin, creatinine, dextrans, and uric acid did not interfere. We compared values for patients’ sera by this method to those by the glucose oxidase/peroxidase-2,2'-azinodiethylbenzothiazoline-6-sulfonic acid, neocuproine, o-toluidine, ferricyanide, and hexokinase methods. For comparisons to the hexokinase method (which we used as a reference method), n = 371, slope = 1.00, y-intercept = 1.57 mg/dl, and bias = 2.05 mg/dl. For the method being evaluated, the run-to-run average monthly standard deviation was 2.9 mg/dl for a control product for which the mean was 85 mg of glucose per deciliter, and 4.3 mg/dl for a product for which the mean was 240 mg/dl. All six methods were compared for effects of uremic sera, icteric sera, and sera from patients receiving ascorbic acid therapy or hypoglycemic drugs.


Key Words: comparison with five other methods for serum glucose • sources of variation • AutoAnalyzer • urinary glucose • normal values • age-related increase in serum glucose • acceptable analytical error, random and systematic • interference studies • " kit" method • Du Pont ACA

Submitted on December 18, 1973
Accepted on February 22, 1974




The following articles in journals at HighWire Press have cited this article:


Home page
 Diabetes CareHome page
S. De Cosmo, R. Trevisan, M. Dalla Vestra, M. Vedovato, A. Argiolas, A. Solini, A. Saller, F. Damone, A. Tiengo, V. Trischitta, et al.
PC-1 Amino Acid Variant Q121 Is Associated With a Lower Glomerular Filtration Rate in Type 2 Diabetic Patients With Abnormal Albumin Excretion Rates
Diabetes Care, October 1, 2003; 26(10): 2898 - 2902.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1974 by the American Association for Clinical Chemistry.