Clinical Chemistry
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Clinical Chemistry 20: 749-752, 1974;
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Clinical Chemistry, Vol 20, 749-752, Copyright © 1974 by the American Association for Clinical Chemistry

Interlaboratory Evaluation of Proficiency Testing in Urinary dgr-Aminolevulinic Acid Analyses

Alexander Berlin 1, Pierre del Castilho 1, and Jan Smeets 1

1 The Commission of the European Communities, 29, Rue Aldringen, Luxembourg, Grand-Duché.

Twenty-six European laboratories have participated in a study of various methods used for determination of dgr-aminolevulinic acid in urine, to determine to what extent they give comparable results when performed by different laboratories. None of the methods as used in the program appeared to be precise and accurate enough to allow each of several laboratories to detect the small differences in urinary dgr-aminolevulinic acid that would result from differences in exposure to environmental lead. Variation among results obtained by different laboratories using the same technique probably reflects differences in the practical experience each laboratory had with the various techniques, rather than intrinsic problems with the methods themselves.


Key Words: lead poisoning • toxicology • interlaboratory comparisons

Submitted on March 8, 1974
Accepted on April 30, 1974






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Copyright © 1974 by the American Association for Clinical Chemistry.