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Clinical Chemistry, Vol 20, 1043-1054, Copyright © 1974 by the American Association for Clinical Chemistry
1 Oak Ridge National Laboratory,4 Oak Ridge, Tenn. 37830.
The Centrifugal Fast Analyzer was used to develop a semiautomated, computerized blood-grouping system. A miniaturized version of the Analyzer was used for the development because, essentially, it enables one to automate "test-tube" grouping procedures. The blood-grouping system is discussed in terms of adaptation of blood-grouping procedures; types of instrumentation used for grouping, cell washing, and Coombs testing; parametric optimization of hemagglutination reactions; subgrouping of A and AB; reverse typing; small-scale blood-grouping evaluation of our approach; and computerization of blood grouping. The data reported here indicate that the system reliably provides accurate results.
Submitted on April 24, 1974
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