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Clinical Chemistry 20: 998-1002, 1974;
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Clinical Chemistry, Vol 20, 998-1002, Copyright © 1974 by the American Association for Clinical Chemistry

Automatic Mass-Spectrometric Analysis: Preliminary Report on Development of a Novel Mass-Spectrometric System for Biomedical Applications

W. J. Dreyer 1, A. Kuppermann 1, H. G. Boettger 1, C. E. Giffin 1, D. D. Norris 1, S. L. Grotch 1, and L. P. Theard 1

1 Division of Biology and Division of Chemistry1 and the Jet Propulsion Laboratory,2 California Institute of Technology, Pasadena, Calif. 91109.

A mass spectrograph, coupled to automatic sample preparation devices and an electro-optical ion detector/ computer system, capable of detecting many ion species simultaneously, presents a promising new approach to biomedical analysis. It will permit simultaneous multicomponent analysis of appropriately prepared samples and may detect as little as 10-15 g of a single component. This approach offers significant advantages over other methods, including conventional mass spectrometry.


Key Words: ultramicro-scale multicomponent analysis

Submitted on April 9, 1974
Accepted on June 11, 1974






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Copyright © 1974 by the American Association for Clinical Chemistry.