Clinical Chemistry
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Clinical Chemistry 20: 1226-1228, 1974;
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Clinical Chemistry, Vol 20, 1226-1228, Copyright © 1974 by the American Association for Clinical Chemistry

Use of Control Sera for Monitoring Temperature Changes during pH and PCO2 Measurements

John P. Manning 1, Daniel N. Sasaki 1, and Paul T. Wertlake 1

1 Department of Laboratories, Saint Barnabas Medical Center, Livingston, N. J. 07039.

We evaluated the temperature coefficients from 25 to 38 °C for aqueous calibration materials, serum (protein-based) control material, and patients’ samples in blood pH measurements and gas analysis. Whereas the aqueous buffers and calibration gases (used as unknowns) were not affected by changing temperature, the temperature coefficients of patients’ samples and protein-based control materials varied similarly to those reported in the literature: 0.011 and 0.014 vs. 0.015 pH/ °C, and 1.76 and 1.57 vs. 1.80 mm Hg/°C. We conclude that the periodic use of suitable control materials can assist in the detection of temperature abnormalities.

Submitted on March 20, 1974
Accepted on May 29, 1974






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Copyright © 1974 by the American Association for Clinical Chemistry.