Clinical Chemistry
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Clinical Chemistry 21: 1567-1571, 1975;
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Clinical Chemistry, Vol 21, 1567-1571, Copyright © 1975 by the American Association for Clinical Chemistry

Single-Channel AutoAnalyzer Adapted for Multiple Tests without Manifold Changes

Z. K. Shihabi 1

1 Department of Pathology, The Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, N. C. 27103

A different approach to continuous-flow analysis is described, in which the initial reagent concentration is adjusted to fit a prefixed manifold while still providing optimum concentrations of the reactants in the mixing coils. A single-channel AutoAnalyzer so designed can perform multiple tests without the need to change manifolds. The system was assembled from a Technicon Sampler II and Pump II, a Gilford 300 N spectrophotometer, and a Varian recorder. Results for calcium, uric acid, glucose, phosphorus, chloride, urea nitrogen, and carbon dioxide, analyzed on this instrument at a speed of 60 samples/ h, compare favorably with those obtained with the AutoAnalyzer 12/60 and 6/60. The instrument is not restricted to certain methodologies and, in addition, can be used manually or for kinetic reactions


Key Words: continuous-flow analysis • analytical systems • pediatric chemistry

Submitted on December 10, 1974
Accepted on June 26, 1975






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Copyright © 1975 by the American Association for Clinical Chemistry.