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Clinical Chemistry 21: 1837-1838, 1975;
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Clinical Chemistry, Vol 21, 1837-1838, Copyright © 1975 by the American Association for Clinical Chemistry

Abnormal Electrophoretic Mobility of a Creatine Kinase MM Isoenzyme

Kimberly Velletri 1, William C. Griffiths 1, and Israel Diamond M.D.1

1 Department of Laboratory Medicine, Roger Williams General Hospital; and Brown University, Department of Biomedical Sciences, Providence, R. I. 02908.

We describe the abnormal electrophoretic mobility of an MM isoenzyme of serum creatine kinase on cellulose acetate, a change evidently attributable to complexing of the enzyme with serum beta-lipoprotein. This complex formation also may lead to difficulty in interpretation of creatine kinase isoenzyme separation by ion-exchange column chromatography.

Submitted on July 10, 1975
Accepted on August 4, 1975







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Copyright © 1975 by the American Association for Clinical Chemistry.