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Clinical Chemistry, Vol 21, 1837-1838, Copyright © 1975 by the American Association for Clinical Chemistry
1 Department of Laboratory Medicine, Roger Williams General
Hospital; and Brown University, Department of Biomedical Sciences, Providence, R. I. 02908.
We describe the abnormal electrophoretic mobility of an
MM isoenzyme of serum creatine kinase on cellulose
acetate, a change evidently attributable to complexing
of the enzyme with serum
-lipoprotein. This complex
formation also may lead to difficulty in interpretation of
creatine kinase isoenzyme separation by ion-exchange
column chromatography.
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