Clinical Chemistry
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Clinical Chemistry 21: 1935-1938, 1975;
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Clinical Chemistry, Vol 21, 1935-1938, Copyright © 1975 by the American Association for Clinical Chemistry

Accurate Estimation of Standard Deviations for Quantitative Methods Used in Clinical Chemistry

Robert W. Burnett 1

1 Clinical Chemistry Laboratory, Hartford Hospital, Hartford, Conn. 06115.

Although the standard deviation is the most widely used measure of the precision of quantitative methods, there is a need to re-examine the conditions necessary to obtain a meaningful estimate of this quantity. The importance of the material to be sampled, the sample size, the calculation of confidence intervals, and the segregation of outliers are discussed.


Key Words: statistics • outliers

Submitted on August 11, 1975




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