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Clinical Chemistry 21: 1961-1963, 1975;
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Clinical Chemistry, Vol 21, 1961-1963, Copyright © 1975 by the American Association for Clinical Chemistry

Temporal Intrapersonal Physiological Variability of Cholinesterase Activity in Human Plasma and Erythrocytes

Frederick R. Sidell 1 and Andris Kaminskis 1

1 Clinical Research Branch, Medical Research Division, Biomedical Laboratory, Edgewood Arsenal, Aberdeen Proving Ground, Md. 21010.

Erythrocyte and plasma cholinesterase activities were measured biweekly in one group of 22 subjects for a year and daily for three weeks in another group of nine men. The average range [i. e., (range/mean) x 100] of activity of erythrocyte cholinesterase in men during a year was 8% and during three weeks was 5%. For plasma, the corresponding values were 25% and 12%. The average ranges for erythrocyte and plasma cholinesterase activity in women during a year were 12% and 24%. Erythrocyte cholinesterase activity varies less than do hematocrit, hemoglobin, or erythrocyte count.

Submitted on August 18, 1975




The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
L. J. Lefkowitz, J. M. Kupina, N. L. Hirth, R. M. Henry, G. Y. Noland, J. Y. Barbee Jr, J. Y. Zhou, and C. B. Weese
Intraindividual Stability of Human Erythrocyte Cholinesterase Activity
Clin. Chem., July 1, 2007; 53(7): 1358 - 1363.
[Abstract] [Full Text] [PDF]


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Copyright © 1975 by the American Association for Clinical Chemistry.