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Clinical Chemistry 21: 300-305, 1975;
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Clinical Chemistry, Vol 21, 300-305, Copyright © 1975 by the American Association for Clinical Chemistry

Lipoprotein Electrophoresis Should Be Discontinued as a Routine Procedure

R. M. Iammarino 1

1 Department of Pathology, Division of Clinical Chemistry, University of Pittsburgh, Pittsburgh, Pa. 15261.

Reviewing our five-year experience with more than 1000 lipid profiles (assays for cholesterol and triglycerides In plasma of fasting patients and lipoprotein electrophoresis of their plasma lipoproteins), I conclude that lipoprotein electrophoresis is superfluous for routine clinical laboratory use, being generally redundant to the other parts of the profile. This conclusion is also prompted in part by recent information that changes our conceptions of lipoprotein metabolism and the clinical expressions of genetic hyperlipoproteinemia. A different approach to lipid profiling is suggested.

Submitted on June 10, 1974
Accepted on December 23, 1974




The following articles in journals at HighWire Press have cited this article:


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[Abstract] [PDF]


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Copyright © 1975 by the American Association for Clinical Chemistry.