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Clinical Chemistry 21: 653-666, 1975;
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Clinical Chemistry, Vol 21, 653-666, Copyright © 1975 by the American Association for Clinical Chemistry

The Prostaglandins in Clinical Medicine. A Developing Role for the Clinical Chemist

Paul T. Russell 1, Andrea J. Eberie 1, and Hsien C. Cheng 1

1 Departments of Obstetrics and Gynecology, Biological Chemistry, and Physiology, University of Cincinnati, Cincinnati, Ohio 45267.

We review the ways that prostaglandins might relate to clinical chemistry. Clinical aspects that are discussed include hypertensive diseases, disorders of the gastrointestinal tract, cancer, inflammation and fever, effects on platelets, the respiratory system and asthma, and reproduction. A survey of procedures for the storage, extraction, separation, and quantitation of the prostaglandins is also presented.


Key Words: history • biosyntheses • metabolism • mechanism of action • analytical methods • clinical correlations • review literature

Submitted on January 6, 1975
Accepted on January 14, 1975






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Copyright © 1975 by the American Association for Clinical Chemistry.