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Clinical Chemistry 21: 853-856, 1975;
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Clinical Chemistry, Vol 21, 853-856, Copyright © 1975 by the American Association for Clinical Chemistry

Direct Method for Measuring Lipoprotein-X in Serum

Wolfgang Neubeck 1 and Dietrich Seidel 1

1 Medical University Hospital, Ludolf-Krehl-Klinik, Bergheimer Strasse 58, D-6900 Heidelberg, G.F.R.

We describe a fast and easy method for routine quantitation of the abnormal lipoprotein, lipoprotein-X. The procedure is based on densitometry of precipitation areas obtained for it after serum electrophoresis in agar gel followed by precipitation with polyanions. The coefficient of variation was less than 3% in one series. Results were linearly related to concentration in the range 0.063 to 6.3 g/liter.


Key Words: cholestasis • lipoprotein-X • "kit" method • diagnostic aids

Submitted on February 12, 1975
Accepted on March 24, 1975






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Copyright © 1975 by the American Association for Clinical Chemistry.