Clinical Chemistry
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Clinical Chemistry 22: 1775-1788, 1976;
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Clinical Chemistry, Vol 22, 1775-1788, Copyright © 1976 by American Association for Clinical Chemistry

Use of gas chromatography and mass spectrometry to analyze underivatized volatile human or animal constituents of clinical interest

IR Politzer, BJ Dowty and JL Laseter

The study of volatilizable components in human and animal samples by gas chromatography and mass spectrometry is reviewed for the years 1970- -1975. Only naturally volatile, underivatized compounds are considered, from sources such as body fluids, tissues, and breath. Where possible, the clinical samples are discussed in terms of normal profiling, aberrations associated with disease states, and specific compound analyses. A brief descriptive technical section is included, stressing types of sample preparation currently being used.




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Copyright © 1976 by the American Association for Clinical Chemistry.