Clinical Chemistry
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Clinical Chemistry 22: 1899-1902, 1976;
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Clinical Chemistry, Vol 22, 1899-1902, Copyright © 1976 by American Association for Clinical Chemistry

Evaluation of enzyme-multiplied immunoassay technique (EMIT) for determination of serum digoxin

AF Rosenthal, MG Vargas and CS Klass

Sixty-seven digoxin-containing sera were analyzed by both radioimmunoassay and EMIT. After some important modifications of the EMIT method, agreement between the two methods was very good. Reproducibility of the EMIT assay was excellent; daily variations in values found for control sera were quite small, and recovery of added digoxin was good. Slight hemolysis hadnegligible effects, but highly hemolyzed specimens gave low recoveries of digoxin.





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Copyright © 1976 by the American Association for Clinical Chemistry.