|
|
||||||||
Clinical Chemistry, Vol 22, 1920-1921, Copyright © 1976 by American Association for Clinical Chemistry
T Gumprecht, DT O'Connor, A Rearden and PL Wolf
A young patient with multiple myeloma was found to have a negative anion gap, with marked asymptomatic hyponatremia. The cause for his negative anion gap is thought to be the myeloma protein, which acts as a cation at physiological pH. Such a hyponatremia responds to reduction in serum concentration of paraprotein and should not be treated by sodium replacement.
The following articles in journals at HighWire Press have cited this article:
![]() |
J. A. Kraut and N. E. Madias Serum Anion Gap: Its Uses and Limitations in Clinical Medicine Clin. J. Am. Soc. Nephrol., January 1, 2007; 2(1): 162 - 174. [Abstract] [Full Text] [PDF] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |