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Clinical Chemistry 22: 221-223, 1976;
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Clinical Chemistry, Vol 22, 221-223, Copyright © 1976 by American Association for Clinical Chemistry

Rapid micromethod for blood lead analysis by anodic stripping voltammetry

G Morrell and G Giridhar

We describe a rapid microscale procedure for blood lead determination by anodic stripping voltammetry. Results correlate well with those obtained by atomic absorption spectroscopy. The procedure involves use of a metal-exchange reagent, which rapidly releases bound lead from its macromolecular binding sites, thus eliminating a long and cumbersome perchloric acid digestion procedure. Reproducibility and analytical recovery of added lead were both excellent. Our results show that anodic stripping voltammetry is a reliable, sensitive micromethod for routine determination of blood lead.


The following articles in journals at HighWire Press have cited this article:


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 J. Pharmacol. Exp. Ther.Home page
D. A. Cory-Slechta, D. J. O'Mara, and B. J. Brockel
Nucleus Accumbens Dopaminergic Medication of Fixed Interval Schedule-Controlled Behavior and Its Modulation by Low-Level Lead Exposure
J. Pharmacol. Exp. Ther., August 1, 1998; 286(2): 794 - 805.
[Abstract] [Full Text]


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Copyright © 1976 by the American Association for Clinical Chemistry.