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Clinical Chemistry 22: 374-378, 1976;
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Clinical Chemistry, Vol 22, 374-378, Copyright © 1976 by American Association for Clinical Chemistry

Evaluation of contemporary methods for serum CO2

JA Lustgarten, RJ Creno, CG Byrd and RE Wenk

We evaluated and inter-compared several newer methods for CO2 analysis-- titrimetric (Van Slyke), automatic titrator, continuous-flow/indicator, and coupled-enzyme procedures--with respect to accuracy, precision, specificity interferences, and management criteria. All methods studied appeared to be clinically acceptable; but precision decreased (standard deviations increased) for the last two methods in above-normal ranges.




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Copyright © 1976 by the American Association for Clinical Chemistry.