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Clinical Chemistry 22: 381-383, 1976;
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Clinical Chemistry, Vol 22, 381-383, Copyright © 1976 by American Association for Clinical Chemistry

Improved method for measuring fibrinogen in plasma, with use of a plasmin inhibitor

LW Steffen and BW Steffen

We describe a modified procedure for quantitating plasma fibrinogen by use of the thrombin-clottable protein technique. The method is accurate and requires a0out 30 min to complete. During its formation and isolation, the clot is protected from the degradative action of plasmin by an inhibitor, epsilon-aminocaproic acid.


The following articles in journals at HighWire Press have cited this article:


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G. Verheyden, J. Matrai, G. Volckaert, and Y. Engelborghs
A fluorescence stopped-flow kinetic study of the conformational activation of {alpha}-chymotrypsin and several mutants
Protein Sci., September 1, 2004; 13(9): 2533 - 2540.
[Abstract] [Full Text] [PDF]


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Copyright © 1976 by the American Association for Clinical Chemistry.