Clinical Chemistry
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Clinical Chemistry 23: 1029-1032, 1977;
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Clinical Chemistry, Vol 23, 1029-1032, Copyright © 1977 by American Association for Clinical Chemistry

Relation between concentrations of free glycerol and triglycerides in human sera

K Stinshoff, D Weisshaar, F Staehler, D Hesse, W Gruber and E Steier

The concentrations of total glycerol, unesterified glycerol, and glycerol deriving from triglycerides (triacylglycerols) were measured in 468 fresh human sera from unselected outpatients of a municipal hospital. The distribution mode of free glycerol was log-normal; that of triglycerides was neither normal nor log-normal. A weak but statistically approved correlation between these variables was demonstrated. A comparison of triglyceride concentrations corrected for unesterified glycerol with those based on total glycerol shows that, for the triglycerides determination, analysis for total glycerol and substraction of 0.11 mmol/liter from the resulting value appears to be justified in clinical routine. Subtraction of individual sample-blank values is unnecessary. In a triglyceride concentration range from 1.71 to 2.85 mmol/liter the 95 percentile for the possible error of this procedure ranges from + 0.04 to - 0.08 mmol/liter.


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