Clinical Chemistry
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Clinical Chemistry 23: 1056-1058, 1977;
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Clinical Chemistry, Vol 23, 1056-1058, Copyright © 1977 by American Association for Clinical Chemistry

Plasma lactate dehydrogenase activity will be increased if detergent and platelets are present

R Bais, MP Prior and JB Edwards

Plasma lactate dehydrogenase activity is artifactually increased when analyzed on the SMAC (Technicon) continuous-flow analyzer. The factors responsible are incomplete centrifugation and the presence of detergent in the dilution buffer. The contribution of platelet lactate dehydrogenase in the plasma is demonstrated with a case of thrombocytosis.




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Copyright © 1977 by the American Association for Clinical Chemistry.