Clinical Chemistry
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Clinical Chemistry 23: 978-981, 1977;
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Clinical Chemistry, Vol 23, 978-981, Copyright © 1977 by American Association for Clinical Chemistry

The beta-lipoprotein doublet in type 3 hyperlipoproteinemia

NK Papadopoulos and PN Herbert

We used a previously reported agarose-gel electrophoresis system to study the lipoprotein patterns in patients with type 3 hyperlipoproteinemia. All samples from 20 subjects tested revealed the presence of two bands with beta-lipoprotein mobility, irrespective of quantitative changes in plasma lipids induced by diet or by the administration of drugs. If these observations are confirmed, the method will permit the diagnosis of type 3 hyperlipoproteinemia without resort to preparative ultracentrifugation and chemical measurement of the very-low-density lipoproteins.


The following articles in journals at HighWire Press have cited this article:


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 J. Lipid Res.Home page
D. J. Blom, P. Byrnes, S. Jones, and A. D. Marais
Non-denaturing polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinemia
J. Lipid Res., January 1, 2003; 44(1): 212 - 217.
[Abstract] [Full Text] [PDF]

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 ANN INTERN MEDHome page
H. B. BREWER Jr., L. A. ZECH, R. E. GREGG, D. SCHWARTZ, and E. J. SCHAEFER
Type III Hyperlipoproteinemia: Diagnosis, Molecular Defects, Pathology, and Treatment
Ann Intern Med, May 1, 1983; 98(5_Part_1): 623 - 640.
[Abstract] [PDF]


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Copyright © 1977 by the American Association for Clinical Chemistry.