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Clinical Chemistry 23: 1548-1550, 1977;
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Clinical Chemistry, Vol 23, 1548-1550, Copyright © 1977 by American Association for Clinical Chemistry

Phospholipid composition of blood plasma, erythrocytes, and "ghosts" in sickle cell disease

HP Schwarz, MB Dahlke and L Dreisbach

We examined the phospholipid composition of the plasma, of whole erythrocytes, and of "ghosts" of the erythrocytes from healthy volunteers, patients with sickle cell disease without crisis, and such patients in crisis, and found that phosphatidylglycerol in the plasma and "ghosts" was very significantly increased in sickle cell crisis but not in the absence of crisis. The significance of these findings is discussed.





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Copyright © 1977 by the American Association for Clinical Chemistry.