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Clinical Chemistry 23: 1679-1683, 1977;
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Clinical Chemistry, Vol 23, 1679-1683, Copyright © 1977 by American Association for Clinical Chemistry

Determination of free thyroxine in serum by radioimmunoassay

NS Jiang and KA Tue

We describe a sensitive and specific radioimmunoassay for free thyroxine, directly determined in the diffusate obtained from equilibrium dialysis of serum. The intra- and interassay precisions were 7.5 +/- 0.27 and 9.1 +/- 0.58 ng/liter (mean +/- SD), respectively. The free thyroxine concentrations of normal persons and patients with thyroid disease were as follows: normal, 7.6 +/- 1.7; euthyroid patients receiving phenytoin, 6.9 +/- 1.4; hypothyroidism, 2.9 +/- 1.3; and hyperthyroidism, 32.3 +/- 12.3 ng/liter (mean +/- SD).


The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
K. S. Fritz, R. B. Wilcox, and J. C. Nelson
A Direct Free Thyroxine (T4) Immunoassay with the Characteristics of a Total T4 Immunoassay
Clin. Chem., May 1, 2007; 53(5): 911 - 915.
[Abstract] [Full Text] [PDF]


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Copyright © 1977 by the American Association for Clinical Chemistry.