Clinical Chemistry
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Clinical Chemistry 24: 157-161, 1978;
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Clinical Chemistry, Vol 24, 157-161, Copyright © 1978 by American Association for Clinical Chemistry

Lipoprotein cholesterol in the serum of children, as determined independently by two different methods

SR Srinivasan, RD Ellefson, CF Whitaker and GS Berenson

We separately evaluated split specimens of serum for lipoprotein cholesterol in 38 five- to 14-year-old children, by the heparin/Ca2+ precipitation method and the ultracentrifugation/dextran sulfate precipitation method. Statistical analysis of the results indicated an excellent agreement (especially in beta- and alpha-lipoprotein cholesterol values) between results by the two methods. The percentage of alpha-lipoprotein cholesterol (mean +/- SD: 38.6 +/- 5.0) in children further confirmed the earlier observations that cholesterol derived from alpha-lipoprotein in children constitutes a relatively greater part of the serum total cholesterol than is true of adults.


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 Arch Pediatr Adolesc MedHome page
J. L. Cresanta, S. R. Srinivasan, L. S. Webber, and G. S. Berenson
Serum Lipid and Lipoprotein Cholesterol Grids for Cardiovascular Risk Screening of Children
Arch Pediatr Adolesc Med, April 1, 1984; 138(4): 379 - 387.
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Copyright © 1978 by the American Association for Clinical Chemistry.