Clinical Chemistry
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 24: 2020-2022, 1978;
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pape, B. E.
Right arrow Articles by Mitra, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pape, B. E.
Right arrow Articles by Mitra, R.

Clinical Chemistry, Vol 24, 2020-2022, Copyright © 1978 by American Association for Clinical Chemistry

Enzyme immunoassay and gas--liquid chromatography compared for determination of lidocaine in serum

BE Pape, R Whiting, KM Parker and R Mitra

Lidocaine, an anti-arrhythmic drug, was quantitated in serum by a commercially supplied enzyme immunoassay procedure. Replicate analyses of serum controls resulted in a within-assay coefficient of variation of less than 5.0 and a between-assay coefficient of variation of less than 6.5. Regression analysis of 87 serum samples analyzed by this technique (y) and by gas-liquid chromatography (x) gave the equation y = 0.96x - 0.03 (r = 0.99). Clinical evaluation of the results indicates the enzyme immunoassay technique to be highly specific and sensitive for lidocaine.


The following articles in journals at HighWire Press have cited this article:


Home page
 ANN INTERN MEDHome page
P. A. ROUTLEDGE, W. W. STARGEL, G. S. WAGNER, and D. G. SHAND
Increased Alpha-1-Acid Glycoprotein and Lidocaine Disposition in Myocardial Infarction
Ann Intern Med, November 1, 1980; 93(5): 701 - 704.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1978 by the American Association for Clinical Chemistry.