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Clinical Chemistry 24: 2132-2134, 1978;
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Clinical Chemistry, Vol 24, 2132-2134, Copyright © 1978 by American Association for Clinical Chemistry

Improved liquid chromatographic determination of placental estriol in urine

GR Gotelli, JH Wall, PM Kabra and LJ Marton

Placental estriol in urine can be determined, after enzymatic hydrolysis, by liquid chromatography. A single-step extraction technique results in rapid processing with minimal sample manipulation. Analytical recovery of estriol added to urine was 96 to 106%. Day-to- day precision (CV), established by 10 replicate analyses at a mean concentration of 15.9 mg of estriol per liter, was 3.7%.




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Copyright © 1978 by the American Association for Clinical Chemistry.