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Clinical Chemistry 24: 230-233, 1978;
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Clinical Chemistry, Vol 24, 230-233, Copyright © 1978 by American Association for Clinical Chemistry

Hemopyrrole and kryptopyrrole are absent from the urine of schizophrenics and normal persons

PL Gendler, HA Duhan and H Rapoport

We describe a method for detecting hemopyrrole and kryptopyrrole in urine, with a detection limit of 100 mug/liter (1 part in 10(7)). Urine is thoroughly extracted with methylene chloride and the extract is concentrated and examined by gas chromatography and gas chromatography- mass spectrometry. No hemopyrrole or kryptopyrrole could be detected in 52 samples, from 17 controls, 29 schizophrenics, and six persons with acute intermittent porphyria.




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Copyright © 1978 by the American Association for Clinical Chemistry.