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Clinical Chemistry 24: 267-271, 1978;
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Clinical Chemistry, Vol 24, 267-271, Copyright © 1978 by American Association for Clinical Chemistry

A practical radioimmunoassay of thyroglobulin

P Bodlaender, JR Arjonilla, R Sweat and SL Twomey

We describe a reliable and convenient double-antibody radioimmunoassay for human thyroglobulin that can be performed within two days. Analytical recoveries were quantitative and immunological equivalence between several sources of human thyroglobulin was demonstrated. Cross reactivity with either thyroxine or triiodothyronine was insignificant. The between-day coefficient of variation in the 5--100 mug/liter range was 10%. The range observed for 68 normal individuals was 2--61 microgram/liter.




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Copyright © 1978 by the American Association for Clinical Chemistry.