Clinical Chemistry
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 24: 531-535, 1978;
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Whicher, J. T.
Right arrow Articles by White, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Whicher, J. T.
Right arrow Articles by White, P.

Clinical Chemistry, Vol 24, 531-535, Copyright © 1978 by American Association for Clinical Chemistry

Method-specific variations in the calibration of a new immunoglobulin standard suitable for use in nephelometric techniques

JT Whicher, J Hunt, DE Perry, JR Hobbs, R Fifield, J Keyser, J Kohn, P Riches, AM Smith, RA Thompson, AM Ward and P White

The putative International Federation of Clinical Chemistry immunoglobulin standard, IFCC 74/1, was calibrated against the World Health Organization (WHO) immunoglobulin standard 67/99 by three different methods: automated immunoprecipitation, Laurell rocket immunoelectrophoresis, and radial immunodiffusion. The same antisera were used in all the assays, which were performed in five expert laboratories. With the aid of linearizing transformations for the dilution curves of both materials and use of a carefully weighted statistical evaluation, values in International Units for IgG, IgA, and IgM were ascribed to IFCC 74/1. The values achieved by the three different methods were not statistically different, except in the case of IgA. IgM assays by automated immunoprecipitation were excluded owing to a high degree of imprecision.


The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
R. M. Rocco
Joachim Kohn (1912-1987) and the Origin of Cellulose Acetate Electrophoresis
Clin. Chem., October 1, 2005; 51(10): 1896 - 1901.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1978 by the American Association for Clinical Chemistry.