Clinical Chemistry
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Clinical Chemistry 24: 627-630, 1978;
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Clinical Chemistry, Vol 24, 627-630, Copyright © 1978 by American Association for Clinical Chemistry

Serum estradiol-17 beta as determined by mass fragmentography and by radioimmunoassay

J Zamecnik, DT Armstrong and K Green

We describe the preparation of [2,4,16,16-2H4]estradiol-17 beta. The method for quantitative determination of subpicomole amounts of estradiol-17 beta (trimethylsilyl ether derivatives) by gas-liquid chromatography-mass spectrometry with multiple ion detector and with [2H4]estradiol-17 beta as the carrier is presented and characterized. Values for serum samples, as measured by radioimmunoassay and by mass fragmentography, agreed well.


The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
H. Wu, C. Ramsay, P. Ozaeta, L. Liu, and H. Aboleneen
Serum Estradiol Quantified by Isotope Dilution-Gas Chromatography/Mass Spectrometry
Clin. Chem., February 1, 2002; 48(2): 364 - 366.
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