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Clinical Chemistry 24: 714-716, 1978;
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Clinical Chemistry, Vol 24, 714-716, Copyright © 1978 by American Association for Clinical Chemistry

Screening for urinary oligosaccharides: application to a mentally handicapped population and to patients with some other diseases

P Purkiss, RC Hughes and RW Watts

The method for screening urinary oligosaccharides described in the accompanying paper [Clin. Chem. 24, 669 (1978)] has been applied to a large group of mentally handicapped patients as well as to patients with cystic fibrosis, malignant disease, and schizophrenia. The cause of the mental handicap was unknown in most cases. The primary object of the study was to investigate a possible link between some diseases and urinary complex carbohydrates. Our results show that abnormalities that are detectable in this way do not contribute significantly to the overall incidence of mental handicap, nor are they expressed in the other diseases studied.





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Copyright © 1978 by the American Association for Clinical Chemistry.