Clinical Chemistry
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Clinical Chemistry 24: 796-799, 1978;
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Clinical Chemistry, Vol 24, 796-799, Copyright © 1978 by American Association for Clinical Chemistry

Improved iodination of peptides for radioimmunoassay and membrane radioreceptor assay

D Heber, WD Odell, H Schedewie and AR Wolfsen

Generally applicable methods for iodinating and purifying small peptide radiolabels for radioimmunoassay and membrane radioreceptor are described in detail. Resulting improvements in radioreceptor assay and radioimmunoassay, as well as results of analyses of specific activity, separation from unlabeled peptide, and storage characteristics, are presented for luliberin, corticotropin, melanotropin, and calcitonin.


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D Heber, R Dodson, R. Swerdloff, K Channabasavaiah, and J. Stewart
Pituitary receptor site blockade by a gonadotropin-releasing hormone antagonist in vivo: mechanism of action
Science, April 23, 1982; 216(4544): 420 - 421.
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Copyright © 1978 by the American Association for Clinical Chemistry.