Clinical Chemistry
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Clinical Chemistry 24: 1167-1169, 1978;
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Clinical Chemistry, Vol 24, 1167-1169, Copyright © 1978 by American Association for Clinical Chemistry

A useful method for predicting creatinine clearance in children

BC Shull, D Haughey, JR Koup, T Baliah and PK Li

A practical method for predicting creatinine clearance for pediatric patients from serum creatinine concentration and patient age is presented. Creatinine excretion rate (ER) can be predicted from the patient's age, in years, by the formula: ER = (0.035 X age) + 0.236. Using the predicted excretion rate and serum creatinine concentration, creatinine clearance can be predicted. There was good correlation (r = 0.90) between predicted and observed creatinine clearances in 101 subjects with various degrees of renal impairment. This method allows renal function to be rapidly estimated.




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Copyright © 1978 by the American Association for Clinical Chemistry.