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Clinical Chemistry, Vol 26, 115-116, Copyright © 1980 by American Association for Clinical Chemistry
A Bouloukos, J Lekakis, J Michael and A Kalofoutis
We determined the concentrations of immunoglobulins A, G, and M in cerebrospinal fluid of 16 patients suffering from multiple sclerosis, 13 with non-bacterial meningitis, 10 with stroke syndrome, and 13 with epilepsy. The differences in concentrations of immunoglobulins in these groups were remarkable in the patients with multiple sclerosis, meningitis, or stroke syndrome. We propose that the determination of the absolute immunoglobulin content in cerebrospinal fluid is of greater significance than the relative immunoglobulin concentration.
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