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Clinical Chemistry 26: 1787-1790, 1980;
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Clinical Chemistry, Vol 26, 1787-1790, Copyright © 1980 by American Association for Clinical Chemistry

Evaluation of baboon antiserum to carcinoembryonic antigen

DE Haagensen Jr, CE Cox, WG Dilley, M Hensley, J Murdoch, ES Newman and SA Wells Jr

The common baboon (Papio), immunized with carcinoembryonic antigen (CEA), was found to form specific-site antibodies for CEA. The baboon antiserum does not recognize colon carcinoma antigen-III, but does demonstrate similar ionic strength effects to those previously described for goat antisera to the CEA-specific site(s). Baboon specific-site antibody for CEA can be used for radioimmunoassay of CEA in plasma and gives similar results to the commercial (Roche) goat anti- CEA.




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