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Clinical Chemistry 26: 1839-1846, 1980;
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Clinical Chemistry, Vol 26, 1839-1846, Copyright © 1980 by American Association for Clinical Chemistry

Gas-chromatographic method of analysis for urinary organic acids. I. Retention indices of 155 metabolically important compounds

K Tanaka, DG Hine, A West-Dull and TB Lynn

Gas-chromatographic retention indices are given, in terms of methylene units, for 155 metabolically important compounds (mostly organic acids) as trimethylsilyl derivatives on 10% OV-1 and 10% OV-17 columns. Comprehensive references on metabolic diseases that can be diagnosed by detection of these metabolites are cross-indexed to facilitate the use of the methylene-unit list. With the data presented here, it is now possible to diagnose more than 25 well-defined organic acidurias by use of gas chromatography alone.


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