Clinical Chemistry
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Clinical Chemistry 26: 1860-1863, 1980;
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Clinical Chemistry, Vol 26, 1860-1863, Copyright © 1980 by American Association for Clinical Chemistry

Changes in transcutaneous oxygen tension during capillary blood-gas sampling

G Graham and MA Kenny

With a Radiometer TCM-1 oxygen monitor, we followed the fluctuations in transcutaneous oxygen tension (ptcO2) during capillary blood collection from a heel prick. Thirty premature infants who presented with some respiratory compromise showed unpredictably increased (43 of 125 observations) or decreased (82 of 125 observations) values during this blood-sampling process. The fluctuation exceeded 10 mmHg in 61 observations and represented as much as -67% relative change. In general, ptcO2 values exceeded capillary pO2 values determined by standard blood-gas analysis. We investigated several aspects of capillary blood sampling to explain these observations. Because the induced response is a dynamic change, which continues throughout the collection process, we conclude that successive specimens will have different O2 tensions. Even if the capillary blood pO2 truly reflected paO2, the magnitude and direction of deviation from the patient's uncompromised O2 tension could lead to inappropriate management. We conclude that capillary blood specimens should not be used for pO2 determinations in newborns.


The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
R. T. Brouillette and D. H. Waxman
Evaluation of the newborn's blood gas status
Clin. Chem., January 1, 1997; 43(1): 215 - 221.
[Abstract] [Full Text] [PDF]

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 Arch Pediatr Adolesc MedHome page
S. E. Courtney, K. R. Weber, L. A. Breakie, S. W. Malin, C. V. Bender, S. Guo, and R. M. Siervogel
Capillary Blood Gases in the Neonate: A Reassessment and Review of the Literature
Arch Pediatr Adolesc Med, February 1, 1990; 144(2): 168 - 172.
[Abstract] [PDF]


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Copyright © 1980 by the American Association for Clinical Chemistry.