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Clinical Chemistry 26: 1890-1895, 1980;
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Clinical Chemistry, Vol 26, 1890-1895, Copyright © 1980 by American Association for Clinical Chemistry

Determination of beta-choriogonadotropin in human plasma; evaluation and comparison of five "kit" methods

BS Knox, JW McKee, PI Hair and JT France

We evaluated five quantitative, commercially available radioimmunoassay methods (Beta-Tec, BIO-RIA, Cambridge Nuclear, Mallinckrodt, and Serono) for rapid determination of the beta-subunit of human choriogonadotropin in serum or plasma. Only three of the kits (Beta- Tec, Mallinckrodt, and Serono) were found suitable for reliable determination of low concentrations of this analyte, which is of importance in the early diagnosis of trophoblastic disease in men and monitoring effectiveness of chemotherapy of trophoblastic tumors in men and women.




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Copyright © 1980 by the American Association for Clinical Chemistry.