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Clinical Chemistry 26: 760-762, 1980;
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Clinical Chemistry, Vol 26, 760-762, Copyright © 1980 by American Association for Clinical Chemistry

Isoenzymes of creatine kinase in extracts of various parts and regions of the human central nervous system

RR Petronia, AH Maas, CW van Veelen and GE Staal

The distribution of isoenzymes of creatine kinase (EC 2.7.3.2.) was investigated by agarose gel electrophoresis of extracts of selected parts and regions of the human central nervous system. Besides the major brain isoenzyme BB, we demonstrated the presence of three other creatine kinase isoenzyme forms. The distribution of creatine kinase isoenzymes depending strongly on the region from which the biopsy was taken. We found substantial amounts of the MB isoenzyme in extracts of the dura from the cauda equina of the two adults examined.




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