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Clinical Chemistry 27: 334-336, 1981;
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Clinical Chemistry, Vol 27, 334-336, Copyright © 1981 by American Association for Clinical Chemistry

Absence of beta-globulin band in the serum protein electropherogram of a patient with liver disease

AO Vladutiu and JS Kim

Agarose-gel electrophoresis of serum of a 72-year-old woman with liver cirrhosis showed virtually no beta-globulins two weeks before the patient's death. There was marked decrease in the concentrations of transferrin, beta-lipoproteins, hemopexin, complement component C3, beta-glycoprotein I, and cholesterol in serum. Absence of a beta- globulin band appears to signify an ominous prognosis.




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Copyright © 1981 by the American Association for Clinical Chemistry.