Clinical Chemistry
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Clinical Chemistry 27: 1157-1164, 1981;
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Clinical Chemistry, Vol 27, 1157-1164, Copyright © 1981 by American Association for Clinical Chemistry

Alternatives to radioimmunoassay: labels and methods

RF Schall Jr and HJ Tenoso

We review the following labels used as substitutes for radioisotopes in immunoassay systems: bacteriophages, chemiluminescence precursors, fluorochromes, fluorogens, fluorescence quenchers, enzymes, coenzymes, inhibitors, substrates, various particulates, metal atoms, and stable free radicals. New methods for performing immunoassays with these labels are described where appropriate. Methods that require no separation steps and offer special promise for easy automation are noted.




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Copyright © 1981 by the American Association for Clinical Chemistry.