Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 27: 1575-1579, 1981;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jolley, M. E.
Right arrow Articles by Kelso, D. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jolley, M. E.
Right arrow Articles by Kelso, D. M.

Clinical Chemistry, Vol 27, 1575-1579, Copyright © 1981 by American Association for Clinical Chemistry

Fluorescence polarization immunoassay. iii. an automated system for therapeutic drug determination

ME Jolley, SD Stroupe, KS Schwenzer, CJ Wang, M Lu-Steffes, HD Hill, SR Popelka, JT Holen and DM Kelso

A fully automated system for performing fluorescence polarization immunoassay has been developed. Reagents for each assay are contained in coded reagent packs, and no reagent reconstitution is required. A common buffer is used for all assays, minimizing changeover and set-up times for each assay. A single sample may be assayed in 5 min, or 20 samples in 10 min. A single-tube blank subtraction for each sample results in highly precise polarization values and obviates sample interferences. We have used this method for assays of gentamicin, theophylline, phenytoin, and phenobarbital. CVs are 1-4%, and the results correlate well with those by other methods. Because of the instrument design and the stability of the reagents, daily calibration is not required; samples may therefore be run immediately upon receipt or batched as desired.


The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
R. Rej
Clinical Chemistry through Clinical Chemistry: A Journal Timeline
Clin. Chem., December 1, 2004; 50(12): 2415 - 2458.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
T Hayashi, Y Ijiri, H Toko, H Shimomura, M Okabe, F Terasaki, Y Kitaura, and K Kawamura
Increased digitalis-like immunoreactive substances in patients with hypertrophic cardiomyopathy
Eur. Heart J., February 2, 2000; 21(4): 296 - 305.
[Abstract] [PDF]

Home page
 Clin. Chem.Home page
N. H. Chiem and D. J. Harrison
Microchip systems for immunoassay: an integrated immunoreactor with electrophoretic separation for serum theophylline determination
Clin. Chem., March 1, 1998; 44(3): 591 - 598.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
R. Jenison, S. Gill, A Pardi, and B Polisky
High-resolution molecular discrimination by RNA
Science, March 11, 1994; 263(5152): 1425 - 1429.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by the American Association for Clinical Chemistry.