Clinical Chemistry
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Clinical Chemistry 29: 164-166, 1983;
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Clinical Chemistry, Vol 29, 164-166, Copyright © 1983 by American Association for Clinical Chemistry

Clinical and laboratory evaluation of a commercial kit for measurement of serum free thyroxin ("Amerlex Free T4")

M Nasralla, M Hassan, AA Al-Ansari, M Kutob, A Al-Abdul Razak and MA Al-Awqati

Different indexes of thyroid function were determined in conjunction with values obtained with a new commercial radioimmunoassay kit for serum free thyroxin, in 49 apparently healthy subjects, 87 pregnant women, and 142 outpatients attending the thyroid clinic. The results indicate a diagnostic success rate of 88% when free thyroxin was measured instead of estimating the so-called free thyroxin index. Furthermore, in three cases of papillary carcinoma the concentration of free thyroxin was increased, although all the other laboratory tests indicated a euthyroid state. Technically, the method is simple, rapid, and precise, and it would be of most value in the small hospital laboratory lacking the facilities of a comprehensive thyroid-function test service.




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Copyright © 1983 by the American Association for Clinical Chemistry.