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Clinical Chemistry 29: 1825-1827, 1983;
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Clinical Chemistry, Vol 29, 1825-1827, Copyright © 1983 by American Association for Clinical Chemistry

Salivary urea nitrogen as an index to renal function: a test-strip method

T Akai, K Naka, C Yoshikawa, K Okuda, T Okamoto, S Yamagami, T Inoue, Y Yamao and S Yamada

To investigate the feasibility of using salivary urea nitrogen as an index of renal glomerular filtration rate, we developed and applied a new analytical system consisting of a urease-containing test strip and an automatic reflectance spectrometer. The concentrations of urea nitrogen so determined correlate well (r = 0.93) with concentrations in serum. These preliminary data suggest that our method can be used routinely as a simple and reliable means of detecting abnormalities of renal function.




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Copyright © 1983 by the American Association for Clinical Chemistry.