Clinical Chemistry
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Clinical Chemistry 29: 369-371, 1983;
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Clinical Chemistry, Vol 29, 369-371, Copyright © 1983 by American Association for Clinical Chemistry

Ion-chromatographic measurement of oxalate in unprocessed urine

M Menon and CJ Mahle

We describe a sensitive, simple technique for determining urinary oxalate. Urine, diluted as necessary with distilled water, is injected into an ion chromatograph. Oxalate is detected conductimetrically as a distinct peak near the tail of the chromatogram. This peak specifically represents oxalate, because it is abolished if the sample is treated with oxalate decarboxylase. We have used this technique to measure oxalate in more than 3000 consecutively received urine samples. It has a CV of 6%.


The following articles in journals at HighWire Press have cited this article:


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 Clin. Chem.Home page
B. G. Keevil and S. Thornton
Quantification of Urinary Oxalate by Liquid Chromatography-Tandem Mass Spectrometry with Online Weak Anion Exchange Chromatography
Clin. Chem., December 1, 2006; 52(12): 2296 - 2299.
[Abstract] [Full Text] [PDF]


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Copyright © 1983 by the American Association for Clinical Chemistry.