Clinical Chemistry
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Clinical Chemistry 29: 1057-1060, 1983;
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Clinical Chemistry, Vol 29, 1057-1060, Copyright © 1983 by American Association for Clinical Chemistry

Serum LD-1 activity in suspected acute myocardial infarction

W Gerhardt, S Hofvendahl, L Ljungdahl, J Waldenstrom, N Tryding, T Pettersson and O Ohlsson

We have studied the diagnostic value of measuring lactate dehydrogenase (LD) isoenzyme 1 in serum of 331 cases of suspected acute myocardial infarction (AMI). At a discriminatory level of 200 U/L (Scandinavian Committee on Enzymes, recommended method for the determination of LD) LD 1 verified the diagnosis in 96% of the AMI cases and excluded it in 96% of the not-AMI cases when samples were drawn 24-72 h after onset of pain. The correlation between 24-h S-LD-1 and 16-h S-CK B activities was 0.94 in the AMI cases. We found that quantitation of serum LD-1 is diagnostically more reliable than the serum LD-1/LD ratio.




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Copyright © 1983 by the American Association for Clinical Chemistry.