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Clinical Chemistry 3: 249-256, 1957;
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Clinical Chemistry, Vol 3, 249-256, Copyright © 1957 by the American Association for Clinical Chemistry

Protein Level in Cerebrospinal Fluid

An Evaluation of Some Methods of Determination

Shirley Sethna 1 and M. U. Tsao 1

1 Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Mich.

Results are given of simultaneous determinations of protein on 17 pooled cerebrospinal fluids (see Table 1) and 22 diluted sera and plasma specimens (see Table 2) by the following methods: micro-Kjeldahl; Johnston-Gibson tyrosine equivalence method; sulfosalicylic acid method; trichloroacetic acid method at 37° and two biuret methods. The micro-Kjeldahl method was used as the standard for comparison.

Submitted on December 22, 1956






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Copyright © 1957 by the American Association for Clinical Chemistry.