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Clinical Chemistry 3: 631-637, 1957;
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Clinical Chemistry, Vol 3, 631-637, Copyright © 1957 by the American Association for Clinical Chemistry

Practical Evaluation of Acid-Base Balance

Herbert P. Jacobi 1, Anthony J. Barak 1, and Meyer Beber 1

1 Department of Biochemistry, University of Nebraska College of Medicine, Omaha, Neb.

The Co2 combining power bears a variable relationship to the in vivo plasma bicarbonate concentration, depending upon the type and severity of acid-base distortion. In respiratory alkalosis and metabolic acidosis the Co2 combining power will usually be greater than the in vivo plasma bicarbonate concentration; whereas, in respiratory acidosis and metabolic alkalosis the Co2 combining power will usually be less. Co2 content, on the other hand, will always parallel the in vivo plasma bicarbonate concentration quite closely, being only slightly greater. These facts, together with other considerations which are discussed, recommend the abandonment of the determination of CO2 combining power.

Submitted on May 17, 1957






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Copyright © 1957 by the American Association for Clinical Chemistry.