Clinical Chemistry
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Clinical Chemistry 30: 116-118, 1984;
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Clinical Chemistry, Vol 30, 116-118, Copyright © 1984 by American Association for Clinical Chemistry

Sex-dependent relation between ionized calcium in serum and blood pressure

N Fogh-Andersen, L Hedegaard, J Thode and O Siggaard-Andersen

In an epidemiological study of 977 45-year-olds, both the mean concentration of ionized calcium in serum, [Ca2+]7.4, and arterial blood pressure were higher in men than in women. Among the men, there was a weak positive correlation between [Ca2+]7.4 and the systolic blood pressure, but no other significant correlation was found within each separate sex. Postmenopausal women had slightly increased [Ca2+]7.4 but normal blood pressure. Patients taking thiazide diuretics or beta-adrenergic blocking agents had normal [Ca2+]7.4.


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 ANN INTERN MEDHome page
D. A. McCARRON and C. D. MORRIS
The Calcium Deficiency Hypothesis of Hypertension
Ann Intern Med, December 1, 1987; 107(6): 919 - 922.
[Abstract] [PDF]

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 ANN INTERN MEDHome page
N. M. KAPLAN and R. B. MEESE
The Calcium Deficiency Hypothesis of Hypertension: A Critique
Ann Intern Med, December 1, 1986; 105(6): 947 - 955.
[Abstract] [PDF]


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Copyright © 1984 by the American Association for Clinical Chemistry.